Despite a 31-point game from senior guard Bridget Carleton, No. 3 seed Iowa State was upset by No. 11 seed Missouri State 69-60 in the round of 32 at Hilton Coliseum in Ames, Iowa.
Iowa State struggled to shoot the ball and only Carleton was able to reach double-digit points. Missouri State had three players with double-digit points and upset their second-straight opponent to advance to the Sweet 16.
Along with her game-high 31 points, Carleton also had 10 rebounds, one assist and a steal.
Of Iowa State's other starters, Alexa Middleton and Ashley Joens both had nine points and five rebounds and Kristin Scott had eight points and six rebounds. Madi Wise had two points and one rebound.
Iowa State's bench combined to score one point while Missouri State had 20 points from their bench.
For Missouri State, Alexa Willard led the team in scoring with 17 points along with five rebounds.
Two other players had double-digit points in Abby Hipp, who had 11 points and four rebounds, and Danielle Gitzen, who had 10 points, six rebounds and five assists.
The Bears shot 41 percent from the floor and 38.9 percent from three during the game.
To contrast, the Cyclones shot 35.6 percent from the floor and 11.8 percent from three.
The team was only able to convert 2-of-17 shots from three. The game marked Iowa State's worst shooting performance from three all season.
The only other time the Cyclones failed to shoot at least 20 percent or higher was against Baylor on February 23. Iowa State lost the game 73-60.
With the Cyclones' season over, Iowa State notably loses Carleton, Middleton and Meredith Burkhall to graduation.
Burkhall served as a role player in the post during the season after beginning the season as a starter. Middleton served as the Cyclones' starting point guard in her only season playing for Iowa State after sitting out last season after transferring from Tennessee.
Carleton ranks second in career points for Iowa State with 2,142 behind Angie Welle, who has 2,149 career points.